Selective Serotonin Reuptake Inhibitors and Violent Crime: A Cohort Study

Selective Serotonin Reuptake Inhibitors and Violent Crime: A Cohort Study

BACKGROUND Although selective serotonin reuptake inhibitors (SSRIs) are widely prescribed, associations with violence are uncertain. METHODS AND FINDINGS From Swedish national registers we extracted information on 856,493 individuals who were prescribed SSRIs, and subsequent violent crimes during 2006 through 2009. We used stratified Cox regression analyses to compare the rate of violent crim...

Selective Serotonin Reuptake Inhibitors

It has long been postulated that a deficiency in CNS serotonergic activity is the cause of, or a predisposing factor for, depression. [1] However, the evidence for this association is largely circumstantial and it certainly does not represent an adequate and full model for depression, probably due to there being multiple aetiological factors. [2] Some pharmacological trial data also cast doubt ...

Selective serotonin reuptake inhibitors.

selective serotonin reuptake inhibitors and cardiovascular events: a systematic review

background: given the importance of the role of depression in predicting the outcome of cardiovascular disorders, current medications for treating depression, particularly selective serotonin reuptake inhibitors (ssris), are taken into  consideration. this study aimed to systematically review the published findings in the use of ssris and the risk for cardiac events. materials and methods: an i...

Selective Serotonin Reuptake Inhibitors: A Class Review

OVERVIEW Many changes and therapeutic advances have occurred in the treatment of depression in recent years, most notably the availability of the selective serotonin reuptake inhibitor (SSRI) class of agents, followed by the introduction of escitalopram oxalate (LexaproTM, Forest), the first agent in what is known as the “second generation” of SSRIs. However, because of the higher acquisition c...